💟 心與腦 顧小培 人工智能研究阿育吠陀醫學

💟不論是中外,舉凡牽涉到感情的事物,都不約而同出動「心」來形容。中文有「傷心」、「痛心」;英文有broken-hearted、heartache。心臟其實只是一個泵,不會思想;情感是感覺的一種,屬腦中的活動,本身與心臟無關。但這(腦中的)活動,能直接影響血液的運行,尤其是運行的速度,能產生「肉體上」physical的衝擊,令心臟有感覺(感到傷、感到痛);另一方面,腦中的活動也須有動力,動力來自養分,養分來自血液。因此,思想要動用心與腦,缺一不可。中國的文字早有清楚闡述,請看「思」這個字,下面是心,上面是「囟」(不是「田」,寫成「田」的樣子,是隸書之後才有的變體)。「囟」是什麼?乃初生嬰兒的頭頂前部,廣東人叫「腦筍」中的「筍」字,正寫就是「囟」。
記憶類似骨骼生長,是一個不停在拆、不停在建的系統。在「建」方面,哥倫比亞大學的Eric Kandel在2000年獲得了諾貝爾醫學及生理學獎,因為他發現記憶的建立,涉及蛋白質合成。不過,記憶本身並非一「舊」蛋白質,而是神經細胞之間建立的一個網路。當一段記憶須「重組」之時,涉及的除了神經細胞,還有膠質細胞(Glial Cells)。膠質細胞的功能之一,是幫助神經細胞回收已分泌了的神經傳導物;功能之二,是提供一個架構,撑起整個神經系統及個別的記憶網絡。所以,一個健全的記憶機制,須包括神經細胞網絡(軟件)和膠質細胞(硬件)。除此之外,還須有基礎建設(Infrastructure)。在這方面,學者發現膠質細胞需要一個乙型澱粉樣蛋白(Beta-Amyloid),用以處理記憶重組(Drugs Aging, Vol. 21, pp. 621-630)。Beta-Amyloid從何而來?來自神經及膠質細胞中的一個前乙型澱粉樣蛋白(APP;全名叫Amyloid Protein Precursor)。
可是,當一個人年紀漸長,不斷受到環境中的氧自由基攻擊,他這個(由APP轉為Beta-Amyloid)的工序會出錯,造出錯體的乙型澱粉樣蛋白。此乃垃圾,本來會被神經及膠質細胞藉一個細胞內部的垃圾處理系統(叫溶蛋白酶體),馬上消化掉(也就是所謂自噬Autophagy)。但自噬與否,關鍵在於一個叫Beclin的蛋白質。一旦Beclin失去了功能,大量垃圾堵塞在神經系統內,可會引致記憶力衰退,及神經細胞自滅,這便是典型老人癡呆症(Alzheimer's Disease)的病徵(J. Clin. Invest., 2008, May 22,電子優先版)。若要防患未然,可以服用補健食品,在「抗氧化」方面,替自己身體補充一般食物之不足。有一個非常安全、非常強力的抗氧化補健食品,叫乙醯半胱胺酸(N-Acetyl Cysteine),可以用以防止老人癡呆(Biol. Chem., Vol. 388, pp. 979-983)。
顧小培-----------------------------

人工智能研究阿育吠陀醫學

人工智能在阿育吠陀醫學研究方面的應用,可以包括以下幾個方面:
數據分析和模式識別:通過機器學習算法,對大量的阿育吠陀醫學文獻、臨床數據進行分析和模式識別,從中發現規律和趨勢,預測疾病的發生和發展趨勢。
診斷和治療支持:人工智能可以幫助醫生更準確地診斷和治療疾病。通過分析患者的病史、癥狀和體征等數據,結合阿育吠陀醫學理論,生成個性化的診療方案。
藥物研發:人工智能可以幫助加速新藥物的研發。通過分析大量的化合物結構、作用機制等數據,預測藥物的活性和毒性,從而減少實驗室試錯的成本和時間。
健康管理和預防:通過監測生物數據和生活方式數據,人工智能可以對個人的健康狀態進行評估和預測,提供個性化的健康建議和預防措施,從而幫助人們保持健康、預防疾病。
總之,人工智能在阿育吠陀醫學研究方面的應用,可以幫助我們更好地理解阿育吠陀醫學理論,提高疾病的診斷和治療水平,促進健康管理和預防工作的開展。

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N-Acetyl Cysteine (NAC) is a form of the amino acid cysteine and is used as a dietary supplement for its potential health benefits. NAC is known for its antioxidant properties and is used to support the body's natural detoxification processes.

Some of the potential health benefits of NAC include:

Liver health: NAC may help to protect the liver from damage caused by toxins, such as alcohol and certain medications.

Respiratory health: NAC has been used to help relieve symptoms of conditions such as bronchitis, chronic obstructive pulmonary disease (COPD), and influenza.

Mental health: NAC has been studied for its potential to reduce symptoms of conditions such as obsessive-compulsive disorder (OCD), depression, and addiction.

Infertility: NAC has been shown to improve sperm quality and increase the chances of pregnancy in couples undergoing assisted reproductive technology (ART) procedures.

It is important to note that while NAC has shown potential health benefits in some studies, more research is needed to fully understand its effects and determine safe and effective dosing guidelines. Additionally, NAC may interact with certain medications, so it is important to talk to a healthcare provider before taking this supplement.

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Alzheimer's disease is a progressive and degenerative brain disorder that affects memory, thinking, and behavior. It is the most common cause of dementia, a condition that affects an individual's ability to perform everyday tasks.

Alzheimer's disease typically affects older individuals and is characterized by a decline in cognitive function, including memory loss, difficulty performing familiar tasks, disorientation, and mood and behavior changes. Over time, the symptoms of Alzheimer's disease become more severe, eventually leading to the need for full-time care.

The exact causes of Alzheimer's disease are not fully understood, but researchers believe that a combination of genetic, environmental, and lifestyle factors may contribute to its development. There is currently no cure for Alzheimer's disease, but medications and other therapies can help to manage symptoms and slow the progression of the disease.

It is important for individuals with Alzheimer's disease and their loved ones to work with a healthcare provider to develop a comprehensive treatment plan that meets their specific needs and helps them to maintain their quality of life for as long as possible.


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